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1. "Illuminating the Druggable Genome", an NIH project focused on accurate data wrangling, processing and analytics for target discovery. IDG shows that there is a knowledge deficit with respect to 2 out of 5 human proteins (see also this NRDD poster, http://www.nature.com/nrd/posters/druggablegenome/index.html). IDG data is available at https://pharos.nih.gov/idg/index 2. DrugCentral is an on-line compendium for drugs and drug targets, which can serve as basis for understanding the molecular basis of therapeutic action. Available at http://drugcentral.org/ 3. The 3 pillars of AI-enabled drug discovery are: drugs, proteins and diseases. We will discuss some efforts in target prioritization for drug discovery based on systemic data integration. Host: Angel Garcia |