Tuesday, April 14, 20151:00 PM - 2:00 PMCNLS Conference Room (TA-3, Bldg 1690)|
In silico Approach for Studying Structure/Function of Biomolecules and Complexes
I will give an overview of our computational works published in scientific journals in the past decade. It is well understood that to understand the details of how a protein function required the knowledge of its structure. While protein structures are routinely solved using x-ray crystallography and NMR (> 100,000 structures in Protein Data Bank), solving structures of large proteins and nucleoprotein complexes is still a grand challenge. Using computational methods and structural knowledge based on various experimental approaches, we can develop detailed structural models (atomic level) of these molecules for a better understanding of how they function.
Host: Kshitij Wagh