William Hlavacek
Executive Committee
CNLS/T-10
Mathmatical Modeling of Complex Biological Systems
Office: TA-3, Bldg. 410, Rm. 136B
Mail Stop: K710
Phone: (505) 665-1355
Fax: (505) 665-3493
wish@lanl.gov
home page
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Educational Background/Employment:
- Ph.D. University of Michigan, 1996
- Postdoctoral Research Associate, Theoretical Biology and Biophysics Group, Theoretical Division, Los Alamos National Laboratory, Los Alamos NM, 1996-2000
- Limited-term Technical Staff Member, Theoretical Biology and Biophysics Group, Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM, 2000-2004
- Adjunct Assistant Professor, Department of Biology, University of New Mexico, Albuquerque, NM, 2003-present
- Technical Staff Member, Theoretical Biology and Biophysics Group, Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM, 2004-present
- Acting Deputy Director, Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, NM, 2006-2007
Research Interests:
- Signal transduction in the immune system
- Biophysics of ligand-receptor binding
- Design principles of bacterial gene regulation
- Metabolomics and metabolic networks in bacteria
Selected Recent Publications:
- M.L. Blinov, J.R. Faeder, B. Goldestein and W.S. Hlavacek,
BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains.,
Bioinformatics 20, 3289-3291 (2004).
- B. Goldstein, J.R. Faeder and W.S. Hlavacek,
Mathematical and computational models of immune-receptor signaling.,
Nat. Rev. Immunol. 4, 445-456 (2004).
- M.E. Wall, W.S. Hlavacek and M.A. Savageau,
Design of gene circuts: lessons from bacteria.,
Nat. Rev. Genet. 5, 34-42 (2004).
- W.S. Hlavacek, J.R. Faeder, M.L. Blinov, A.S. Perelson and B. Goldstein,
The complexity of complexes in signal transduction.,
Biotechnol. Bioeng. 84, 783-794 (2003).
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