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Ludmil B. Alexandrov

Oppenheimer Fellow
T-6/CNLS

Theoretical Biology & Biophysics

Ludmil B. Alexandrov

Office: TA-3, Bldg 1690, Room 142
Mail Stop: B258
Phone: +1 (505) 667-1646
Fax: +1 (505) 665-2616

lba@lanl.gov
home page

Research highlight
 Educational Background/Employment:
  • B.Sc. (2007) Computer Science, Neumont University
  • M.Phil. (2010) Computational Biology, University of Cambridge
  • Ph.D. (2014) Cancer Genomics, University of Cambridge
  • Employment:
    • 2004-2006 Research Student, Los Alamos National Laboratory
    • 2007-2010 Research Associate, Harvard Medical School
    • 2010-2014 Ph.D. Student, Wellcome Trust Sanger Institute
    • 2014-current Oppenheimer Fellow, Los Alamos National Laboratory

Research Interests:

  • Cancer Genomics
  • Mutagenesis
  • Ageing
  • Biophysics
  • Bioinformatics

Selected Recent Publications:

  1. Alexandrov LB Understanding the origins of human cancer, Science 350 (6265), 1175-1177 (2015).
  2. Alexandrov LB et al. Clock-like mutational processes in human somatic cells, Nature Genetics 47 (12), 1402–1407 (2015).
  3. Alexandrov LB et al. A mutational signature in gastric cancer suggests therapeutic strategies, Nature Communications 6 (8683) (2015).
  4. Alexandrov LB and Stratton MR Mutational signatures: the patterns of somatic mutations hidden in cancer genomes, Current Opinion in Genetics & Development 24, 52-60 (2014).
  5. Alexandrov LB et al. Signatures of mutational processes in human cancer, Nature 500 (7463) 415-421 (2013).
  6. Alexandrov LB et al. Deciphering Signatures of Mutational Processes Operative in Human Cancer, Cell Reports 3 (1) 246-259 (2013).
  7. Nik-Zainal S, Alexandrov LB et al. Mutational Processes Molding the Genomes of 21 Breast Cancers, Cell 149 (5) 979-993 (2012).

    Complete list of publications
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