Hans Frauenfelder
Senior Fellow
T-10/CNLS
Protein Sciences
Office: TA-03, Building 0483, Room 120
Mail Stop: K710
Phone: (505) 665-2547
Fax: (505) 665-3493
frauenfelder@lanl.gov
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Educational Background/Employment:
- Dr. sc. nat. 1950, Swiss Federal Institute of Technology. ZŸrich, Switzerland.
- 1952-1992 Department of Physics University of Illinois at Urbana-Champaign.
- 1992-LANL
Research Interests:
- I have been interested in a broad range of fields. My thesis concerned surface physics, even including neutrino recoil. I then discovered perturbed angular correlation (PAC), a field that is still active today. After coming to the US in 1952, I switched to nuclear physics, studied parity violation, and used the Mšssbauer effect to investigate a number of topics. The Mšssbauer effect led to the investigation of biomolecules, in particular proteins. These studies, initially only a sideline, were so interesting that they expanded into a more approach and, today, I am deeply involved in exploring the connections among the structure, dynamics, and function of proteins. My guess is that such studies will form a major branch of physics (Òbiological physicsÓ) for many years to come.
Selected Recent Publications:
- H. Frauenfelder, G. A. Petsko and D. Tsernoglou,
Temperature-dependent X-ray diffraction as a probe of protein structural dynamics,
Nature 280, 558-563 (1979).
- H Frauenfelder. S. G. Sligar and P. G. Wolynes,
The Energy Landscapes and Motions of Proteins,
Science 254, 1598-1603 (1991).
- H. Frauenfelder, P.G. Wolynes, and R.H. Austin,
Biological Physics,
Rev. Mod Phys. 71, S419-S430 (1999).
- P. W. Fenimore, Hans Frauenfelder, B. H. McMahon, and R. D. Young,
Bulk-solvent and hydration-shell fluctuations, similar to alpha- and beta- fluctuations in glasses, control protein motions and functions,
Proc. Natl. Acad. Sci. USA. 101, 14409-14413, (2004).
- P. W. Fenimore, H. Frauenfelder, B. H. McMahon, R. D. Young,
Proteins are paradigms of stochastic complexity,
Physica A 351, 1 Ð 13 (2005).
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