Lab Home | Phone | Search
Center for Nonlinear Studies  Center for Nonlinear Studies
 Colloquia Archive 
 Postdoc Seminars Archive 
 Quantum Lunch 
 CMS Colloquia 
 Q-Mat Seminars 
 Q-Mat Seminars Archive 
 Kac Lectures 
 Dist. Quant. Lecture 
 Ulam Scholar 
 Summer Research 
 Student Application 
 Past Visitors 
 PD Travel Request 
 History of CNLS 
 Maps, Directions 
 CNLS Office 
Tuesday, May 08, 2012
1:30 PM - 3:00 PM
Physics Auditorium, TA-3, SM-215


CNLS KAC Lecture: Self-Replication Without Life

Paul Chaikin
New York University

We want to make a “non-biological” system which can self-replicate. The idea is to design particles with specific and reversible and irreversible interactions, introduce seed motifs, and cycle the system in such a way that a copy is made. Repeating the cycle would double the number of offspring in each generation leading to exponential growth. Using the chemistry of DNA either on colloids or on DNA tiles makes the specific recognition part easy. In the case of DNA tiles we have in fact replicated the seed at least to the third generation. The DNA linkers can also be self-protected so that particles don’t interact unless they are held together for sufficient time – a nano-contact glue, and we have discovered a new type of topological interaction associated with concatenation of DNA loops which gives a Velcro-like binding. Chemical modification of the DNA allows us to permanently crosslink hybridized strands for irreversible bonds and a new type of photolithography. We have also designed and produced colloidal particles that use novel “lock and key” geometries to get specific and reversible physical interactions.

Host: Robert Ecke, CNLS, 667-1444,