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Ming Zhang

Postdoctoral Researcher
CNLS/T-6

System Biology

Ming Zhang

Office: TA-3, Bldg 1690, Room 142
Mail Stop: B258
Phone: (505) 665-6604
Fax: (505) 665-2659

mingzh@lanl.gov
home page

Research highlight
     Educational Background/Employment:
    • Ph.D (2007) Bioinformatics, Faculty of Mathematics, University of Goettingen, Germany. Summa Cum Laude.
    • Employment:
      • 2001-2002 Binformatics Intern (ORISE Postgraduate Fellow), US Centers for Disease Control and Prevention.
      • 2002-2007 Research Assistant, T-6, LANL.
      • 2007-present Postdoctoral Associate, T-6, LANL.
      • 2008-present Postdoctoral researcher, CNLS, LANL.

    Research Interests:

    • System biology of viruses and their human host.

    Selected Recent Publications:

    1. AK. Schultz, M. Zhang, I. Bulla, B. Korber, T.Leitner, B. Morgenstern, M. Stanke. Improved HIV subtyping in jpHMM.
      Nucleic Acids Reserach. W647-51. 2009.
    2. SS. Kulkarni, A. Lapedes, H. Tang, S. Gnanakaran, MG Daniels,M. Zhang,T. Bhattacharya, M. Li, VR. Polonis, FE. McCutchan, L. Morris,D. Ellenberger, ST. Butera, RC. Bollinger, BT. Korber, RS. Paranjape, DC. Montefiori. Highly complex neutralization determinants on a monophyletic lineage of newly transmitted subtype C HIV-1 Env clones from India.
      Virology.385(2):505-20. 2009.
    3. AK. Schultz, M. Zhang, T. Leitner, B. Korber, B. Morgenstern, M. Stanke. jpHMM: Erkennung von Rekombinationen bei HIV.
      BIOforum. 2/2008, 44-46.
    4. G. Didier, L. Debomy, M. Pupin, M. Zhang, A. Grossmann, C. Devauchelle, I. Laprevotte. Comparing sequences without using alignments: Application to HIV/SIV subtyping.
      BMC Bioinformatics.8(1):1. 2007.
    5. J. Xie, M. Zhang, T. Zhou, X. Hua, L. Tang, W. Wu. Sno/scaRNAbase: a curated database for small nucleolar RNAs and cajal body-specific RNAs.
      Nucleic Acids Research. 35:D183-D187. 2007.
    6. M. Li, JF.Salazar-Gonzalez, CA.Derdeyn, L.Morris, C.Williamson, JE.Robinson, JM.Decker, Y.Li, MG.Salazar, VR.Polonis, K.Mlisana, S.Karim, K.Hong, KM.Greene, M.Bilska, J.Zhou, S.Allen, E.Chomba, J.Mulenga, C.Vwalika, F.Gao, M.Zhang, B.Korber, E.Hunter, BH.Hahn, DC.Montefiori. Genetic and neutralization properties of acute and early subtype C human immunodeficiency virus type 1 molecular env clones from heterosexually acquired infections in Southern Africa.
      Journal of Virology. 80(23):11776-90. 2006.
    7. JJ. Esposito, S. Sammons, A. Frace, J. Osborne, M. Olsen-Rasmussen, M. Zhang, D. Govil, I. Damon, R. Kline, M. Laker, Y. Li, G. Smith, H. Meyer, J. LeDuc, R. Wohlhueter. Genome sequence diversity and clues to the evolution of variola virus.
      Science. 313(5788):807-812. 2006.
    8. M. Zhang, A. Schultz, C. Calef, C. Kuiken, T. Leitner, B. Korber, B. Morgenstern, M. Stanke. jpHMM at GOBICS: a web server to detect genomic recombinations in HIV-1.
      Nucleic Acids Research. 34:W463-5. 2006.
    9. A.-K. Schultz, M. Zhang, T. Leitner, C. Kuiken, B. Korber, B. Morgenstern, M. Stanke. A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes.
      BMC Bioinformatics. 7:265. 2006.
    10. C. Calef, C. Kuiken, J. Szinger, B. Gaschen, W. Abfalterer, M. Zhang, N. Tao, R. Funkhouser, K. Yusim, M. Flynn, A. Dalwani, B. Foley, W. Bruno, T. Leitner, B. Korber. Gateway to tools of the HIV and HCV databases.
      In HIV Molecular Immunology. p33-56. 2005. Korber et al, editors. Publisher: Los Alamos Natl Lab, Theoretical Biology and Biophysics, Los Alamos, New Mexico. LA-UR 06-0036.
    11. M. Zhang, K. Wilbe, N. Wolfe, B. Gaschen, J. Carr, T. Leitner. HIV-1 CRF13-cpx revisited: identification of a new sequence from Cameroon and signal for sub-subtype J2. AIDS Research and Human Retroviruses. 21(11):955-960. 2005.
    12. M. Zhang, B. Gaschen, W. Blay, B. Foley, N. Haigwood, C. Kuiken, B. Korber. Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV Envelopes, and Influenza Hemagglutinin.
      Glycobiology. 14(12):1229-1246. 2004.
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