Cesar Lopez BautistaCNLS Postdoctoral Research Associate CNLS/Unknown My study area is unknown Office: TA-3, Bldg 1690, Room 000 Mail Stop: B258 Phone: (505) 000-0000 Fax: (505) 665-2659 unknown@lanl.gov home page Research highlight- Immunology signaling and lipid dependency
- Photosystem complexes and NPQ improvement
- Cellulose and its application in biofuels
- HIV and vaccine development
- Biophysical chemistry of biological membranes
| | Educational Background/Employment:- B.S. (2003) Sciences with mayor in Biology and Biochemistry, Universidad Peruana Cayetano Heredia, Perú
- M.S. (2008) Laureate Biomolecular sciences (Top master), Rijkuniversiteit Groningen, The Netherlands
- Ph.D. (2012) Biophysical chemistry, Rijkuniversiteit Groningen, The Netherlands
- Employment:
- 2002-2003 Laboratory of cellular biology. Universidad Peruana Cayetano Heredia Lima-Peru, Research assistant
- 2003-2006 Laboratory of infectious diseases. Universidad Peruana Cayetano Heredia Lima-Peru, Research assistant
- 2003-2006 Laboratory of bioinformatics and computational biology. Universidad Peruana Cayetano Heredia, Lima Peru
- 2004-2006 Teacher assistant biochemistry department. Universidad Peruana Cayetano Heredia, Lima-Peru
- 2012-2013 Postdoctoral fellowship, MD group. Rijkuniversiteit Groningen. Groningen-The Netherlands
- Professional Training:
- 2004-2006 Teacher assistant biochemistry department. Universidad Peruana Cayetano Heredia, Lima-Peru
- 2012-2013 Postdoctoral fellowship, MD group. Rijkuniversiteit Groningen. Groningen-The Netherlands
Research Interests: - My research specialization is in the field of structural biology and computational biophysics, with emphasis in molecular dynamic simulations of different bio constitutes (e.g. Lipids, proteins, carbohydrates). I aimed to understand biologically relevant processes involving all sorts of bio-molecules from knowledge of their pairwise interactions.
Selected Recent Publications: - H. Ingolfsson, C.A. López, J.J. Uusitalo, D.H. de Jong, S. Gopal, X. Periole, S.J. Marrink The power of coarse-graining in biomolecular simulations, WIREs: Comp. Mol. Sci. 4,225-248 (2014).
- C.A. López, A.H. de Vries, S.J. Marrink Computational microscopy of cyclodextrin mediated cholesterol extraction from lipid model membranes, Sci. Rep. 3,2071 (2013).
- López CA, Sovova Z, van Eerden FJ, De Vries AH, Marrink SJ Martini force field parameters for glycolipids, J. Chem. Theory Comput. 9,1694-1708 (2013).
- López CA, De Vries AH, Marrink SJ Amylose folding under the influence of lipids, Carbohydr. Res. 364C,1-7 (2012).
- hendrik de Jong D, López CA, Marrink SJ Molecular view on protein sorting into liquid-ordered membrane domains mediated by gangliosides and lipid anchors, Faraday Discuss. 161,347-363 (2012).
- López CA, De Vries AH, Marrink SJ Molecular Mechanism of Cyclodextrin Mediated Cholesterol Extraction, Plos Comput. Biol. 7,e1002020 (2011).
- Quiliano M, Gutierrez AH, Gilman RH, López CA, Evangelista W, et al. Structure-Activity relationship in mutated pyrazinamidases from Mycobacterium tuberculosis, Bioinformation 6,335-339 (2011).
- Zimic M, Gutierrez AH, Gilman RH, López CA, Quiliano M, et al. Immunoinformatics prediction of linear epitopes from Taenia solium TSOL18, Bioinformation 6,271-274 (2011).
- Vujicic-Zagar A, Pijning T, Kralj S, López CA, Eeuwema W, et al. Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes, Proc Natl Acad Sci USA 107,21406-21411 (2011).
- López CA, Rzepiela AJ, De Vries AH, Dijkhuizen L, Huenenberger PH, et al. Martini Coarse-Grained Force Field: Extension to Carbohydrates., J. Chem. Theory Comput. 5,3195-3210 (2009).
- Zimic M, Pajuelo M, Rueda D, López CA, Arana Y, et al. Utility of a protein fraction with cathepsin L-Like activity purified from cysticercus fluid of Taenia solium in the diagnosis of human cysticercosis, Am. J. Trop. Med. Hyg. 80,964-970 (2009).
- Zimic MJ, Infantes J, López CA, Velasquez J, Farfan M, et al. Comparison of the peptidase activity in the oncosphere excretory/secretory products of Taenia solium and Taenia saginata, J. Parasitol. 93,727-734 (2011).
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