Modeling aspects of solid cancer growth

From Q-bio

One of the challenges in systems biology is how to incorporate detailed intracellular level dynamics into fully integrated cell and tissue level models. Here we will present some alternative methods for doing this in the context of cancer growth. We will consider somatic evolution in ductal carcinoma in situ, homeostatis and instability in colorectal cancer, and vascular tumour growth. In each case we will use hybrid cellular automata approaches.