Implications of Dynamic Scaffolding for Signaling Efficiency in Drosophila Phototransduction

From Q-bio

Drosophila phototransduction converts information about light contrast into an electrical signal through G protein signaling. We recently identified that the visual scaffold InaD undergoes a light-driven conformational change which is predicted to affect binding of the activator molecule phospholipase C. This dynamic scaffolding event is predicted to affect the probability of generating a response to light using two different models.