View source for Noisy out of necessity: the relationship among gene circuit architecture, dynamics and biological function

Cellular processes are typically controlled by gene regulatory circuits
that are comprised of interactions among genes and proteins.  However,
the functional importance of a particular pattern of interactions
(architecture) that constitutes a genetic circuit remains poorly
understood.  I will present research that aims to investigate the
relationship among gene circuit architecture, dynamics and function.  We
find that these gene circuit properties are linked by their
susceptibility to stochastic behavior.  Environmental constraints may
thus select for gene circuit architectures based on their
architecture-dependent noise profiles.