Defending against anthrax: Cell membrane channels and drug design

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By Dr. Ekaterina Nestorovich, Staff Scientist, National Institutes of Health

March 17, 2009

Santa Fe Complex

Abstract
Anthrax causes disease by secreting proteins that form channels or openings on the surface of a host target cell. These channels allow toxins to enter the host cell and ultimately cause disease. Understanding channel structure and function can lead to small-molecule drugs that block the actions of anthrax toxins.

Dr. Nestorovich will be introduced by Dr. Michael E. Wall, Staff Scientist, Los Alamos National Laboratory.

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