Agenda

FRIDAY

Morning                Registration table open

14:45-15:00           Welcome and introductory remarks

15:00-15:45           Siegfried Musser (Texas A&M)
Single Molecule Studies of Nucleocytoplasmic Transport

15:45-16:30           Cees Dekker (Delft)
Single-molecule transport across an individual biomimetic
nuclear pore complex

16:30-17:00           Break

17:00-17:45           Weidong Yang (Bowling Green State)
Three-Dimensional Distribution of Transient Interactions in the
Nuclear Pore Complex Obtained from Single-Molecule Snapshots

17:40-18:15           Jan Liphardt (UC Berkeley)
Single-molecule Studies of Nuclear Import

                         Dinner on your own

SATURDAY

8:00-9:00               Breakfast

9:00-9:45               Michael Rexach (UC Santa Cruz)
Architecture of the Nuclear Pore Complex Transporter

9:45-10:30             Steffen Frey (Max Planck)
Functional principles of the nuclear pore permeability barrier

10:30-11:00           Break

11:00-11:45           Ajay Gopinathan (UC Merced)
Polymer Brushes and the Nuclear Pore:
Implications for a Novel Form of Gated Transport

11:45-18:30            Reiner Peters (Rockefeller)
Analysis and use of the nuclear pore complex transport mechanism
by nanotechnology

12:30-14:30           Lunch/discussions on your own

14:30-15:15           Lucy Colwell (Harvard)
Effects of charge on the NPC selectivity

15:15-16:00           Roderick Lim (Basel)
The influence of FG-domain surface density
on the binding avidity of Kaps

16:00-16:45           Liesbeth Veenhoff (Groningen)
Unfolded linkers slice through the nuclear pore complex
during membrane protein transport

19:00 and on         Posters and discussion over buffet dinner and drinks

SUNDAY

8:00-9:00               Breakfast

9:00-9:45               Karsten Weis (UC Berkeley)
Mechanism of Dbp5 activation by Gle1 and the small molecule
IP6 in mRNA export

9:45-10:30             Dirk Gorlich (Max Planck)
Redefinition of the consensus for classic nuclear export signals by
structures of PKI-type and Rev-type NESs bound to the exportin CRM1

10:30-11:00           Break

11:00-11:45           Yosef Gruenbaum (Hebrew University)
Regulation of gene position and activity by the nuclear lamina
Implications for a Novel Form of Gated Transport

11:45-12:30           Patrick Lusk (Yale)
Transport of nucleoporins to the daughter bud cortex
during membrane protein transport

12:30-14:30           Lunch/discussions on your own

14:30-15:15           Anurag Sethi (Los Alamos)
Conformational Characterization of Intrinsically Disordered
Regions in Proteins

15:15-16:00           Michael Elbaum (Weizmann)
Substrate competition in nucleocytoplasmic exchange

16:00-16:45           Anton Zilman (Los Alamos)
Quantitative analysis of transport through the NPC
and associated artificial nano-channels

19:00-21:00           Banquet dinner and "Round table" discussion


                              Workshop ends

MONDAY