Agenda
Updated 11/4/09
Sunday, January 10th
Session 1 - Systems approaches in innate and humoral immunity
Chairs: Steven Kleinstein, Stephanie Forrest
9:30-9:40 Introduction
9:40-10:10 Bridget Wilson (UNM): High Resolution Technologies Capture FceRI Organization and Receptor Dynamics: the Need for Spatial Stochastic Simulation Approaches
10:10-10:40 Aaron Dinner (U Chicago): Genetic circuit architectures underlying choice of effector B cell fates
10:40-11:10 Phil Hodgkin (WEHI, AU): B-cell differentiation: order from manipulating randomness
11:30-12:00 Martin Meier-Schellersheim (NIH): Automated quantitative analysis and computational reconstruction of 3D fluorescence microscopy data – application to lymphocyte data
Session 2 - Contributed Talks on Systems approaches in immunity
Chairs: Vitaly Ganusov and Ruy Ribeiro
14:30-14:55 Anu Chaudhary (LANL): Studying protein-protein interactions underlying the innate immune response
14:55-15:20 Raibatak Das (UBC): Extraction of membrane-receptor binding kinetics from single-particle tracking data
15:20-15:45 Bin Hu (UNM): A model of early events in T-cell receptor signaling
15:45-16:10 Ramit Mehr (Bar-Ilan University): B Cell mutation and selection in autoimmune disease as inferred from mutation analyses of immunoglobulin variable region genes
16:10-16:35 German Nudelman (Mount Sinai, NY): Agent-based tripwire model explains paradoxical response to virus infection in human dendritic cells
Plenary Session
Chairs: Miles Davenport and Phil Hodgkin
18:00-19:00 Bali Pulendran (Emory): Systems approaches to dissect immunity following vaccination with the yellow fever vaccine.
Monday, January 11th
Session 3 - Systems approaches in cellular immunity
Chairs: Rob De Boer and Alan Perelson
9:00-9:30 Dan Coombs (UBC): A TCR/pMHC confinement-time model of T-cell activation
9:30-10:00 Rustom Antia (Emory): Modeling the dynamics persistent infections
10:00-10:30 Miles Davenport (UNSW, AU): Decision making during T cell responses
11:00-11:30 Thorsten Mempel (Harvard): T cell migratory dynamics during an anti-tumor immune response
11:30-12:00 Jurgen Westermann (Luebeck, GE): Principles of T-cell migration: Facts and fiction
Session 4 - Contributed talks on Systems approaches in
cellular immunity
Chairs: Rustom Antia and Bridget Wilson
14:30-14:55 Becca Asquith (Imperial College): What determines the outcome of HTLV-1 infection?
14:55-15:20 Fred Adler (Utah): No one remembers when the second team wins: strategies of rhinovirus immune manipulation
15:20-15:45 Stanca M Ciupe (Duke): Models of antibody responses during HIV infection
15:45-16:10 Paul Thomas (St. Jude’s): Memory potential is determined by priming epitope number
16:10-16:30 Coffee Break (Santa Fe Room)
16:30-16:55 Jose Borghans (Utrecht): Naive T-cell dynamics in mice and men: Recent thymic emigrants revisited
16:55-17:20 Iren Bains (University College London): Heterogeneity within thymic emigrants: a mechanistic explanation for T cell homeostasis?
17:20-17:45 Irina Grigorova (UCSF): T-cell recirculation through mouse lymph nodes: insights from 2-photon imaging, quantitative analysis and modeling of T-cell egress
17:45-18:10 Rob De Boer (Utrecht): Analyzing immune cell migration
Poster Session
Mathematical Model of a Three-Stage Innate Immune Response to Pneumococcal Lung Infection - Amber Smith
Cooperation and competition determine CD8 T-cell immunodominance hierarchies- Andreas Handel
Evolving and Quenching a Quorum in Digital Organisms - Benjamin E. Beckmann and Philip K. McKinley
A comparative study of seasonal and non-seasonal dynamics of Buruli ulcer - Bonsu Osei
MHC-I Molecules Exploit the Low G+C Content of Pathogenic Genomes for Increased Presentation -
Jorg Calis, Gabino Sanchez-Perez & Can Kesmir
Stochastic modelling of T cell repertoire diversity -
Carmen Molina-Paris
Modeling the Impact of Proliferation and Attrition on the Memory T-Cell Repertoire -
Courtney Davis
Interpreting Labeling Data Set of CFSE and Thymidine on Division Histories of B Cells -
Ha Youn Lee
Mathematical and computational modeling of the replication kinetics of swine-origin, avian,and seasonal influenza strains. -
Hugh Mitchell, Drew Levin, Catherine Beauchemin, Alan Perelson, Stephanie Forrest, Fred Koster
Predicted Confounding Effect of Weakly Immunogenic Long-Lived Infected Cells on Vaccination against Simian Immunodeficiency Virus - Igor Rouzine
A stochastic model of and viral load and viral blips in HIV patients on ART - Jessica Conway
How natural host species avoid CD4+ T cell depletion: insights into the pathogenesis of HIV - Ming Liang Chan, Petravic, J., Ortiz, A., Engram, J., Paiardini, M., Cromer, D., Silvestri, G., Davenport, M. P.
Mathematical models of persistent infections - B. Kochin, Philip Johnson, J. Blattman, R. Regoes and R. Antia
New analytical approaches for measuring SLOW dynamic processes in immune disorders - Robert Busch
Mathematical modelling of lymphopenia induced proliferation - Andrey Shuvaev, Thea Hogan, Daniel Commenges, Andrew Yates, Robin Callard, Ben Seddon, Rodolphe Thiébaut
In vivo quantification of the effect of IL-7 on proliferation, survival and production of CD4+T cells: mathematical analysis of one phase I study in HIV-1 infected patients. - Rodolphe Thiébaut , Drylewicz J, Lacabaratz C, Lelievre JD, Chêne G, Beq S, Croughs T, Commenges D, Delfraissy JF, Levy Y
Immune System Decision-Making by Detection of Pathogen Growth - Sharon Bewick
Understanding HIV Genetic Diversity - A Population Genetics Approach - Sivan Leviyang
Immune Systems as Complex Learning Machines - Terran Lane and Melanie Moses
A combined mathematical modelling and experimental investigation of naïve T lymphocyte homeostasis - Thea Hogan, Andrey Shuvaev, Andrew Yates, Rodolphe Thiebaut, Robin Callard and Benedict Seddon
Multi-Scaled Stochastic Simulation of Cell-to-Cell Signaling - Yishai Shimoni, German Nudelman, Jianzhong Hu, Fernand Hayot, James G. Wetmur, and Stuart C. Sealfon
Myasthenia Gravis Ig gene lineage trees and mutation analyses - Neta S. Zuckerman, Wendy Howard, Sonia Berrih-Aknin, Jacky Bismuth, Hanna Edelman, Kate Gibson, Deborah Dunn-Walters Ramit Mehr
